Human leucocytic antigen status in Egyptian pregnant women with preeclampsia

ABSTRACT

Sixty preeclamptic together with one hundred and fifty normal Egyptian pregnant women were invtstigated as regards the human leucocyuc antigen [HLA] system. Out of the sixty women with pree-clampsia, 7 [11.66%] had only one identical detectable antigen [i.e. homozygous] at B locus while 42 [28%] out of the one hundred and fifty normal control had one identical antigen detected. This tendency of preeclamptic, than normal control, to be heterozygous at the B locus did not apply to the A or D related loci. No specific HLA, A, B, or DR antigen occurred more commonly in the preeclamptic patitnts