Synthesis and uterotrophic activity of 2-substituted estradiol and ring A fused pyranone and furanone derivatives
Alexandria Journal of Pharmaceutical Sciences. 1994; 8 (2): 95-9
in English
| IMEMR
| ID: emr-31594
ABSTRACT
Several new modified estradiol analogs have been synthesized and examined as potential estrogens. Nuclear modification involved the introduction of various substituents at the 2-position of estradiol and fusion of a heterocylic ring to position 2, 3 of ring A of the steroidal nucleus. Uterine weight assays in rats have shown that all tested compounds produced a moderate increase in uterine weight
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pyrans
/
Furans
Language:
English
Journal:
Alex. J. Pharm. Sci.
Year:
1994
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