Synthesis and characterization of some [t] 1- [substituted amino or piperidino] -1-phenylethanes: novel bioisosteric relatives of pcp
Alexandria Journal of Pharmaceutical Sciences. 1994; 8 (3): 215-7
in English
| IMEMR
| ID: emr-31646
ABSTRACT
The fact that phencyclidine [PCP]-receptors have been involved in the binding interactions with other hallucinogens, such as sigmaopiates, initiated the idea of synthesizing some novel bioisosteric relatives of PCP. Such compounds would act as potential blockers for central PCP-receptors, and thus might be utilized in the discouraging drug abusers or the therapeutic treatment of the hallucinogenic symptoms of such abused agents. The suggested compounds are 1-[substituted amino or piperidino]-1-phenylethane derivatives
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Ethane
Language:
English
Journal:
Alex. J. Pharm. Sci.
Year:
1994
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