Intra-articular bupivacaine versus morphine for postoperative analgesia after arthroscopic knee surgery

ABSTRACT

Sixty adult patients were randomly collected and divided into two equal groups. One group received general anesthesia using thiopentone sodium, halothane and nitrous oxide in oxygen and spontaneous ventilation, the other group received spinal analgesia [2 ml of 0.5% bupivacaine]. Each group was subdivided into three equal groups [10 patients each]. Group A received intra-articular saline, group B received intra-articular morphine, and group C received intra-articular bupivacaine. Analysis of the results revealed that both morphine and bupivacaine provided a better analgesic effect when compared with saline group. They also prolonged the duration first analgesic use and reduced the analgesic requirements. The effect of morphine was significant when compared with that of bupivacaine