Prevalence of hepatitic C virus antibodies in chronic liver disease, hepatitis, hepatocellular carcinoma and rheumatoid arthritis
EJMM-Egyptian Journal of Medical Microbiology [The]. 1994; 3 (1): 29-36
in English
| IMEMR
| ID: emr-32260
ABSTRACT
The prevalence of antibodies to hepatitis C virus [Anti-HCV] has been measured using HCV EIA 2 second generation test in 97 patients with chronic liver disease [CLD], hepatitis, hepatocellular carcinoma [HCC] and rheumatoid arthritis [RA]. 45 normal subjects served as control. 46.15% of 39 patients with CLD were positive for anti-HCV, while 64.7% of 17 patients with hepatitis showed positive antibodies to HCV. In HCC, 60% of 15 patients were positive to anti-HCV. Interestingly, 36.4% of 26 patients with RA having positive rheumatoid factor showed positive antibodies to HCV and 11.1% of normal controls were positive to anti-HCV. HBsAg was positive in 20.5% in CLD and in 47% in hepatitis group, while 40% of HCC patients showed positive HBsAg. Low prevalence of HBsAg was found in RA and controls [3.8% and 4.4% respectively]. Our study revealed that HCV has a role in causation of hepatitis, hepatocellular carcinoma and chronic liver disease in our locality. Also, cross-reactivity between antibodies to HCV and other antibodies [rheumatoid factors] may occur
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Arthritis, Rheumatoid
/
Chronic Disease
/
Prevalence
/
Carcinoma, Hepatocellular
/
Hepatitis C Antibodies
/
Hepatitis
/
Liver Cirrhosis
/
Liver Diseases
Type of study:
Prevalence study
Limits:
Humans
Language:
English
Journal:
Egypt. J. Med. Microbiol.
Year:
1994
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