Synthesis and antihypertensive evaluation of some phthalazines containing 1,3,4-thiadiazines and 1,3,4-thiadiazin-5-ones
Egyptian Journal of Pharmaceutical Sciences. 1994; 35 (1-6): 257-266
in English
| IMEMR
| ID: emr-32400
ABSTRACT
Starting from methyl N2[4-methylphthalazin-1-yl]dithiocarbazinate, a number of new phthalazine derivatives containing 1, 3, 4-thiadiazine and 1, 3, 4-thiadiazin-5-one rings were prepared. The structure of the new products was confirmed by spectral analysis besides synthesis via other routes. A preliminary antihypertensive evaluation revealed that most compounds possess moderate antihypertensive activity
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Thiadiazines
/
Antihypertensive Agents
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
1994
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