8-Hydroxyglucosylharmine from the Egyptian peganum harmala L seeds

ABSTRACT

8-hydroxyglucosylharmine was isolated from the methanolic extract of the Egyptian Peganum harmala L. seeds. This glucosidic beta-carboline alkaloid is of common occurrence in seedling and callus derived from roots and hypocotyls, but it is a rare and minor alkaloid of the seeds. The present isolation of 8-hydroxyglucosylharmine represents the first isolation of this alkaloid from the Egyptian P. harmala L. seeds. Moreover, harmine, harmaline, harmol, and harmalol were also isolated. The structure of the isolated alkaloids were established from their physicochemical characters and spectral data