Serum bile acids and standard liver enzymes in hepatobiliary disorders

ABSTRACT

The study included 20 normal individuals as control group and 58 cases [13 cases with hepatitis, 17 cases with chronic cholycystitis, 14 cases with obstructive jaundice and 14 cases with hepatoma]. The mean value of serum levels of postprandial bile acids and standard liver enzymes for each diseased group showed statistically significant difference except in ALP, GGT and 5'N in chronic cholycystitis group when compared with the control group. The sensitivity and accuracy of serum postprandial bile acids were 100% and 97% in both hepatoma and obstructive jaundice groups. While in hepatitis were 100% and 96%, and as regard the cases of chronic cholycystitis were 23.5% and 62%, respectively