Prospective non-randomized trial for the evaluation of anti-estrogen agent [tamoxifen] in the palliation of patients with unrespectable hepatocellular carcinoma
Medical Journal of Cairo University [The]. 1994; 62 (Supp. 4): 239-245
in English
| IMEMR
| ID: emr-33636
ABSTRACT
This is a prospective non-randomized trial including 14 patients suffering from unresectable hepatocellular carcinoma who attended Kasr El Aini Center for Radiation Oncology and Nuclear Mcdicine [NEMROCK], from January 1991 till January 1994. All patients received the anti-estrogen Tamoxifen [TAM], as a palliative treatment. The maximum survival was 24 months [two patients], and the minimum survival was three months [five patients]. The maximum duration of subjective response was 18 months, and the minimum duration of subjective response was two months. There was an objective response evidenced by a drop of the median level of serum alpha-fetoprotein. The drop in serum alpha fetoprotein was maintained for 6 months in 12 patients and in two patients, it was maintained for 18 months
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Palliative Care
/
Tamoxifen
/
Carcinoma, Hepatocellular
/
Liver Function Tests
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
Language:
English
Journal:
Med. J. Cairo Univ.
Year:
1994
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