Some liver function studies in post traumatic cases receiving total parenteral nutrition

ABSTRACT

Twenty patients with post traumatic coma admitted to I.C.U. were studied for liver functions. Fat free TPN therapy was given and some of the liver function tests were performed on five occasions. SAP, SGPT, SGOT and LDH showed a significant increase after 7, 14, and 21 days. Total serum proteins showed a significant decrease after 7, 14, and 21 days, while albumin also decreased significantly after 14 and 21 days. Balanced parenteral nutrition regimen consisting of dextrose vamin and intralipid supplemented by minerals, electrolytes, vitamins, co-factors and micronutrients is recommended for critically ill patients. Liver functions evaluation is essential in cases undergoing TPN therapy