Histopathological changes in nasal mucosa following corrective surgery for chronic nasal obstruction in allergic and vasomotor rhinitis

ABSTRACT

Histopathological nasal mucosal changes, in allergic and vasomotor rhinitis, before and 6 months after corrective nasal surgery were recorded in order to determine any light microscopic variations in these patients and to assess the effects of corrective nasal surgery; performed to relieve nasal obstruction, on the microscopic structure of nasal mucosa. A total of 64 cases of allergic and vasomotor rhinitis suffering from chronic nasal obstruction due to either septal or conchal causes were included in this study. 26 patients were diagnosed as allergic and the remainder as vasomotor rhinitis on the basis of history, thorough clinical examination, skin testing and total serum IgE levels. The results indicated that differentiation between allergic and vasomotor rhinitis on histopathological basis was not substantiated. Postoperative changes in both groups were similar and demonstrated a significant change towards normality