Factors affecting premenstrual tension syndrome [PMS] and the value of pyridoxine in its management

ABSTRACT

This study included 230 females with premenstrual tension syndrome [PMS], compared to 250 females forming the non-PMS group. The results showed that educational level, working condition, marital status, parity and contraceptive methods are all involved in the development of PMS. The diagnosed symptoms of premenstrual tension were more common among singles, students, secondary and highly educated females, and married women with one or two pregnancies, who use the IUD as a contraceptive method, and who is breast fed. These factors provide the patient criteria to allow for early intervention to control further complications and to carry out early measures for prevention. The double blind placebo-controlled part evaluated pyridoxine as a treatment for PMS. Pyridoxine did not relieve the symptoms to a statistically significant level, nor did it significantly affect the level of patients' serum prolactin, however, it improved some behavioral symptoms