significance of anticardiolipin antibodies in recurrent abortion

ABSTRACT

The levels of anticardiolipin antibodies were investigated in the sera of 40 women with recurrent spontaneous unexplained abortion, coming for antenatal care. The difference in AC values between patients and control was statistically insignificant. Also, no difference of significance was observed between primary and secondary aborters. However, the incidence of AC positivity rose as the number of abortions increased, a finding of statistical significance [r = 309, P < 02]. Platelet counts tended to be lower in the patients group irrespectively to category, yet without statistical significance. AC positivity was exclusive to the GPL fraction of anticardiolipins. The significance of AC antibodies in recurrent unexplained abortion is further confirmed, with assertion of the importance of GPL over MPL