Curative effect of bone marrow transplantation on irradiated liver and plasma proteins

ABSTRACT

The histopathological examination of mice liver exposed to whole body gamma irradiation [6 Gy] followed by bone marrow transplantation [BMT], showed a moderate degree of recovery after 20 days. Parallel electrophoretic analysis of plasma proteins revealed significant increase only in alpha and gamma-globulins. Accordingly, it could be assumed that BMT ameliorated partially the liver histopathology and the level of certain plasma proteins after 20 days, so it could be considered as a convenient therapy following whole body gamma- irradiation