Immunophenotyping of T-lymphocyte subsets in hepatic schistosomiasis with or without hepatitis B virus infection
New Egyptian Journal of Medicine [The]. 1994; 11 (5): 1660-63
in English
| IMEMR
| ID: emr-34887
ABSTRACT
Chronic human infection with Schistosoma mansoni trematodes is associated with impaired cell immunity. Granuloma formation and its modulation represent a delicate balance between T lymphocyte subsets, T helper and T suppressor cells. The lymphocytes identified were of pan T cell type CDT3 and showed marked CDT4 cells [helper/inducer] than CDT8 cells in granuloma formation and its modulation. The study showed a significant correlation between the degree of fibrosis and T helper cell levels which implies the role of the T helper pathogenesis of hepatic fibrosis. There was no significant difference between pure schistosomal group and the mixed one as regard T-lymphocyte subsets. It seems that the immunological events in both diseases were different
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Schistosomiasis
/
Immunophenotyping
/
Hepatitis B
/
Liver Diseases, Parasitic
Limits:
Humans
Language:
English
Journal:
New Egypt. J. Med.
Year:
1994
Similar
MEDLINE
...
LILACS
LIS