Genodermatoses

ABSTRACT

This study included 40 cases with various skin manifestations with a possible genetic background. Their ages ranged from 4 days to 12 years. All cases were subjected to detailed history taking with a pedigree done and a thorough general medical examination with special emphasis on the neurological and dermatologic examination [skin, mucous membrane, hair, nails and teeth]. Special investigations done were Fundus examination [9 cases], intelligence quotient [14 cases], electroencephalogram [13 cases], computed brain tomograms [11 cases], abdominal ultrasonography [5 cases], determination of serum immunoglobulins [Ig A, E, G] and alpha fetoprotein [one case] and skin biopsy [7 cases]. Results are presented in tables and figures and discussed