Evaluation of epicoprostanol: a major sterol of ambergris for anti-inflammatory and antipyretic activities
Pakistan Journal of Pharmacology. 1994; 11 (2): 65-72
in English
| IMEMR
| ID: emr-35102
ABSTRACT
The major sterol of epicoprostanol was isolated from ambergris by flash column chromatography. Its identity as epicoprostanol was confirmed by 1H - NMR and 13C - NMR spectroscopy. Epicoprostanol was studied for its anti - inflammatory and antipyretic activities. Epicoprostanol produced a significant inhibition of carrageenan induced paw oedema. The study on antipyretic activity showed, that epicoprostanol produced a significant reduction of yeast - induced hyperthermia in rat
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Anti-Inflammatory Agents
Language:
English
Journal:
Pak. J. Pharmacol.
Year:
1994
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