effect of induction agent diprivan on intraocular pressure in comparison with thiopentone

ABSTRACT

Propofol [Diprivan] has been used as an induction agent to reduce and control, the intraocular pressure in 21 patients of both sexes [16 males and 5 females] ranging in age from 18 - 66 years. They were undergoing elective ophthalmic surgery. Its effects have been compared with 20 patients induced with thiopentone. The effect of suxamethonium and intubation on IOP were studied in the two groups of patients using applanation tonometer. Diprivan proved to be a very satisfactory agent that produce a significant fall in IOP and was significantly more effective than thiopentone in this respect. Also propofol attenuate the increase in IOP before intubation and appear to be the drug of choice in ophthalmic surgery which required smooth induction of anaesthesia and effective control of IOP