Reductive debromination of erythro-2,3-dibromo-1-cyclopropyl-3- [p-substituted phenyl] -1-propanones

ABSTRACT

Reductive debromination of erythro-2,3-dibromo-1-cyclopropyl-3-[p- substituted phenyl]-1-propanones was carried out with sodium thiophenoxide in 1 2 molar ratio in absolute ethanol. All dibromides gave the same product; namely, trans-1-cyclopropyl-3-[p- substituted phenyl]-2-propanones. The configuration of the obtained products was assigned by PMR spectra. The possible reaction mechanism was presented