Synthesis and pharmacological screening of certain substituted tetrahydropyrido [4,3-b] quinolines and pyrazole [4,3-c] quinolines
Bulletin of Faculty of Pharmacy-Cairo University. 1995; 33 (1): 33-9
in English
| IMEMR
| ID: emr-36693
ABSTRACT
The synthesis of two series of annulated quinoline derivatives III and IV is presented. Pyrazolo [14,3-c] quinoline derivatives [IV] were also obtained by a newly reported rearrangement reaction [17]. The analgesic antipyretic as well as anti-inflammatory activities of 7-chloro-2 [benzothiazol-2-yl]-4 [2N-ethylamino] ethyl]-2H-pyrazolo [4,3-c] quinoline [IV6], 7-chloro-2 [benzothiazol-2-yl]-4 [2 N-propylamino] ethyl]-2H-pyrazolo [4,3-c] quinoline [IV6], 7-chloro-2 [benzothiazol-2-yl]-4[2 N-propylamino] ethyl]-2H-pyrazolo [4, 3-c] quinoline [IV12], 7-chloro-2 propyl-1,2,3,4-tetrahydropyrido [4,3-b] quinoline [III7] and 7-chloro-4 [2[N-ethylamino] ethyl]-2[4-hydroxy-6-methylpyrimidin-2-yl]-2H-pyrazolo [4,3-c] quinoline [IV3] have been investigated
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Quinolines
/
Anti-Inflammatory Agents
Type of study:
Screening study
Limits:
Animals
Language:
English
Journal:
Bull. Fac. Pharm.-Cairo Univ.
Year:
1995
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