Serum fructosamine and lipids profile in children with acute lymphocytic leukemia

ABSTRACT

Serum lipid fractions [TC, TG, HDL, LDL and VLDL] and AF concentrations were estimated in twenty newly diagnosed leukemic children prior to initiation of therapy and ten healthy controls. The leukemic patients showed highly significant increase in TC, TG, HDL, LDL and VLDL values [p< 0.005] with highly significant decrease in HDL value [p< 0.005] compared to control. The fructosamine value showed significant decrease compared to control [p< 0.005]. The results suggest an abnormality in systemic lipid metabolism and abnormal serum protein turnover