Peritoneal wash along with prophylactic amoxicillin-clavulanic acid [augmentin] versus gentamicin with metronidazole

ABSTRACT

20 patients with about 100 mls or less contaminated peritoneal fluid were washed with 4 liters of normal saline and 3 doses of 1.2 Grams IV Augmentin in 24 hours post operatively. Only one patient's wound became septic [5%] and another two patients had pyrexia [10%] with no definite infective focus, as compared to 25% abdominal sepsis and 35% significant post operative pyrexia in 20 cases treated with Metronidazole and Gentamicin as prophylactic antibiotics for 7 days without peritoneal wash