Blood lymphocytes energy metabolism in myocardial inflammatory injuries

ABSTRACT

Cytochemical analysis and bioenergetics of blood lymphocytes have been studied in 68 patients of Infectious Allergical Myocarditis [IAM] and 44 patients of Myocardiosclerosis [MC]. Regarding cellular metabolism, the activity of Glucose-6-PO4 Dehydrogenase [G-6-PD] [E.C. I.I.I.49] was found to be high according to the Nitrobluetetrazolium Reduction Test [I] due to the disturbance of NAD and NADP diaphorase [E.C.I.6.4.3]. The activity of L-glycerophosphate Dehydrogenase [E.C.I.1.1.8, 1.1.99.5] and cytochrome C content of the cells was found to be reduced. Thus, study of energy metabolism of blood lymphocytes provides an additional differential characteristics of inflammatory injuries of myocardium