Correlation between cervical and endometrial pathology in menopausal women

ABSTRACT

This study was conducted on three hundred postmenopausal women aged between 45-70 years and divided into three groups Non-bleeding normal postmenopause, postmenopausal bleeding group and hormone replacement therapy group. All cases were subjected to D and C biopsy, colposcopic examination and pap. Smear of the cervix and suspicious cervix cases were subjected to cervical biopsy. Atrophic endometrium was the most common pattern in non-bleeding group [70%], endometrial hyperplasia [cystic, adenomatous] was the mostly detected pattern in the postmenopausal bleeding group [45%]. In patients receiving hormone therapy, the commonest endometrial pattern was secretory one [66%]. As regards to colposcopic and pap. Smear of the cervix, cervical atrophic changes were the most common finding in non- bleeding group [36%]. Chronic cervicitis and atrophic changes were found in 43%and 39%; respectively, in postmenopausal bleeding group. In patients receiving hormone therapy, cervical infection was found in 26% and atrophic changes were found in 20%. This may be related to estrogenic effects