Saponins from Randia nilotica [STPF] and their biological evaluation

ABSTRACT

Two triterpenoidal saponins were isolated from R and ia nilotica Stem [Rubiaceae] for the first time. The genin of each saponin was established as oleanolic acid, identified by physical and chemical evidence. The saponin mixture exerted antimicrobial activity against Gram +ve and Gram -ve bacteria. Moreover, the molluscicidal test against Biomphalaria alexandria snails the intermediate hosts for the parasite Schistosoma mansoni was carried out, the LC50, LC98, slope function and the 95% confidence limits were determined