Biosynthesis of demethyltetracycline by a strain of streptomyces
Egyptian Journal of Microbiology. 1996; 31 (2): 237-255
in English
| IMEMR
| ID: emr-40758
ABSTRACT
Streptomyces aureofaciens sub-species viridulaus [isolate No. MN 27] was found to produce a yellowish orange pigment. This pigment was extracted from the fermentation medium by chloroform at neutral pH [pH 7], chromatographically purified and obtained as orange powder. The purified pigmented substance exhibits a strong antimicrobial activity towards Gram positive and Gram negative bacteria [MIC =200, 50, 5, 100, 35 ug/ml against B. Subtilis, B. Megaterium, B. Cereus, Athrobacter simplex, and E. coli, respectively]. The physicochemical characteristics of the purified substance were investigated and accordingly the present antibiotic pigment was identified as a new antibiotic belonging to tetracycline group of antibiotics having indicator properties for which the name demethyltetracycline was suggested
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Streptomyces aureofaciens
/
Actinomyces
/
Anti-Bacterial Agents
Language:
English
Journal:
Egypt. J. Microbiol.
Year:
1996
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