Reactions of uridine and 4-thiouridine derivatives with some-halo esters
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 291-302
in English
| IMEMR
| ID: emr-40799
ABSTRACT
Uridine and 4-thiouridine were converted into the corresponding 2,3-o-isopropylidene-5-thiocyanato derivatives. Then, each resulted derivative was reacted individually with both of ethyl alpha- chloroacetoacetate, ethyl alpha-bromobenzoylacetate and ethyl bromo pyruvate. Furthermore, these 5-thiocyanato products were transformed into the corresponding 5-mercapto analogues. The produced analogues were undergo ring formation to give the corresponding 4,5-cyclized pyrimidine derivatives
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Thiouridine
/
Uridine
/
Esters
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
1996
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