Synthesis of some aminonaphthalene and 5-substituted uracil nucleosides derivatives

ABSTRACT

Some amino naphthalene nucleosides were prepared by the reaction of both of 1-amino, 1-aminomethyl, 1,5-diamino and 2,6-bis [aminomethyl] naphthalene derivatives with 2,3,5-tri-O-acetyl ribofuranosyl chloride. On the other hand, the reactions of 2',3'-O-isopropylidene 5-amino uridine and its 5-aminomethyl analogue with gluconolactone and the reactions of 2',3'-O-isopropylidene-5-chloromethyl uridine with sodium N-methyl taurinate have been described