Anti-inflammatory activity of Solanum nigrum Linn. Berries

ABSTRACT

50% alcoholic and pet. ether extract of Solanum nigrum L. [Berries] were investigated for anti-inflammatory activity in carrageenin induced edema in albino rats. The alcoholic extract showed significant activity on inhibition of edema while the activity shown by the petroleum ether extract was comparatively less significant. Solanum nigrum Linn. Is commonly used in Indian System of Medicine. It has been reported to possess hepatoprotective, antiseptic, antispasmodic, immunodulating and anticonvulsant activities. The chemical constituents separated out from the berries are reported to be steroidal glycoalkaloids solamargine, solasonine and solanigrine steroidal genin [titogenin], saponinus and vitamins [riboflavin, carotene, nicotinic acid and ascorbic acid]