efficacy of ivermectin in treating rabbits experimentally infected with eimeria as indicated parasitologically and histologically

ABSTRACT

Ivermectin [Ivomec] was used as coccidiocidal drug against Eimeria in experimentally infected rabbits as indicated parasitologically and histologically. 20 Bosskat rabbits were divided into 5 groups, 3 groups were inoculated with 1000 sporulated oocysts and the other 2 groups were kept as negative controls with and without Ivermectin administration. Ivermectin [1 10] was injected subcutaneously in a dose of 0.5 ml in animals of groups 1, 2 and 3. The treatment of group 1 was on the 4th day A.I. and on the 4th day and 7th day A.I. in group 2. The treated animals with one or two doses showed mild coccidiosis with very few numbers of oocysts deposition and rapid intestinal regeneration with degenerated eimerial developmental stages, especially the asexual ones