Biotransformation of alpha santonin
Mansoura Journal of Pharmaceutical Sciences. 1996; 12 (1): 99-109
in English
| IMEMR
| ID: emr-41979
ABSTRACT
Bacillus cereus UI-1477 was able to convert alpha-santonin into 1,2-dihydrosantonin in a 64% yield. The chemical identity of the obtained metabolite was confirmed by UV, IR, 1D- and 2D-, 1H- and 13C-NMR spectroscopy. Biological evaluation showed a complete loss of both anthelmintic and antimicrobial activity of 1,2-dihydrosantonin in comparison to alpha-santonin
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Biological Availability
/
Santonin
/
Anti-Infective Agents
Language:
English
Journal:
Mansoura J. Pharm. Sci.
Year:
1996
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