TIVA: comparative study between different techniques

ABSTRACT

This study was carried out on 60 adult patients of both sexes with age ranged between 20 and 50 years, they underwent surgical procedures that were expected to last about one hour. Patients were allocated into three equal groups. Each group was subjected to a different anesthetic techniques. The concentration of cortisol and glucose increased in the three different groups during surgery and further significant increase was observed on recovery. This indicated that the three different groups were subjected to comparable stress. There was little difference in the recovery time between the three groups as assessed by Steward coma scale. Although the ketamine-midazolam group and the propofol-ketamine group showed a slightly longer duration for recovery, this is due to the re-entry of ketamine from the peripheral to the central compartment. Also, propofol was effective in eliminating the side effects of the subanesthetic doses of ketamine