Role of cytogenetic study in diagnosis and management of primary gonadal failure

ABSTRACT

The present study investigates the clinical, cytogenetic and hormonal features of patients with primary gonadal failure aiming to define the role of cytogenetic study in their diagnosis and management. 30 patients were included in this study. They all had hypogonadism, elevated gonadotropin levels and streak or hypoplastic gonads by sonography. From the results obtained it was concluded that karyotyping is most useful in any patient with delayed sexual development, elevated serum gonadotropins and streak gonads