Synthesis and reactions of some 1,2,4-oxadiazole derivatives for biological evaluation
Egyptian Journal of Chemistry. 1984; 27 (4): 515-23
in English
| IMEMR
| ID: emr-4271
ABSTRACT
3-Aryl-l,2,4-oxadiazole-5-thiol [I] reacted with maleic acid and some of its derivatives to give 2-[3-aryl-l,2, 4-oxadiazole-5-yl-thio] succinic acid derivatives [II] and [III]. Compound [la] reacted with benzoquinone to give [IV]. 5-Amino-3-phenyl-l,2,4-oxadiazole [V] reacted with certain acid chlorides to give 5-acylamino derivatives [VI]. Compounds [VIII] were prepared by the reaction of compounds [VII] with some amines. Compound [VHIf] condensed with several aromatic aldehydes to give 5-[p-cinnamoyl-anilino]-3-phenyl-l,2,4-oxadiazole [IX]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Biological Availability
Language:
English
Journal:
Egypt. J. Chem.
Year:
1984
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