Atrial natriuretic peptide in children with nephrotic syndrome
New Egyptian Journal of Medicine [The]. 1996; 14 (5): 244-48
in English
| IMEMR
| ID: emr-42713
ABSTRACT
Plasma levels of atrial natriuretic peptide [ANP] were measured using a specific and sensitive radioimmunoassay in 40 children with nephrotic syndrome [NS]. Nine patients were steroid resistant and the remaining had primary steroid responsive NS. Renal biopsy was performed to four steroid resistant nephrotic patients and revealed membranoproliferative glomerulo nephritis [MPGN] in three patients and lupus nephritis in one patient. Plasma levels of ANP were also measured in 18 healthy children as a control group. High plasma concentrations of ANP were detected in nephrotic patients during active stage of the disease [edema and heavy proteinuria] irrespective to the underlying renal pathology or to the response to steroid therapy. Plasma ANP values in nephrotic patients correlated negatively with serum albumin and with serum creatinine clearance
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Child
/
Atrial Natriuretic Factor
/
Nephrosis, Lipoid
/
Nephrotic Syndrome
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
New Egypt. J. Med.
Year:
1996
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