Hemodynamic effects of different modes of positive pressure mechanical ventilation

ABSTRACT

Many patients admitted to the ICU are in need for mechanical ventilation. Ventilators directly affect cardiovascular performance by changing either lung volume or intrathoracic pressure. As oxygen delivery to various organs is the product of regional blood flow and oxygen content, the effect of different modes of positive pressure ventilation on circulatory dynamics and oxygen transport are to be compared. From the results obtained it was concluded that positive pressure ventilation had adverse effects on circulatory dynamics. Choosing the optimal ventilatory mode as well as the best weaning policy should be guided by the underlying clinical state and followed up hemodynamically by noninvasive, and if necessary, invasive means