Induction labour with prostaglandin E[2] vaginal tablets

ABSTRACT

Prostaglandins E[2] and F[2] alpha cause softening and bring about uterine contractions and are used to induce labour or abortion being given by various routes. For the past few years 3 mg of vaginal tablets of Prostaglandin E[2] have become available in Pakistan. To assess the efficiency of this preparation in induction of labour in Pakistani women, a prospective study was carried out in 50 patients 40 multigravida 10 primigravidas. After ascertaining the indication for induction and ruling out any contraindication to vaginal delivery, 3 mg vaginal tablet of prostaglandin E[2] was placed in the vagina. If labour did not initiate, the tablet was repeated at six hour intervals for a total dose of 9 mg. There was significant softening of the cervix. Thirty one of the 40 multigravida and six of the 10 primigravida delivered within 24 hours giving a success rate of 75% and 60% respectively. The authors conclude that induction of labour with prostaglandin E[2] vaginal tablets is a safe and simple method giving a good success rate without undue side effects