Carcinoma of gall bladder

ABSTRACT

To determine the incidence, clinical presentation and management of Carcinoma of gall bladder. Design: A prospective study of 20 cases of histologically proved Carcinoma gall bladder found in 230 cases of gall bladder disease operated from January 1993 to December 1994. Settings Surgical department Liaquate Medical College Hospital, Jamshoro, Hyderabad. Subjects: Twenty cases of Carcinoma of gall bladder. Main outcome measures: Clinical features, investigations, management and follow up of the patients. The mean age of patients was 50 years and female to male ratio was 4 to 1. Clinical presentation was 90% had pain right hypochondrium, 50% had lump right hypochondrium and 20% had jaundice. Investigation were not helpful in the diagnosis. Fourteen cases underwent cholecystectomy, 1 partial cholecystectomy and 5 cases had biopsy only. All cases died within 6 months expect incidentally found carcinoma gall bladder. Early cancer is asymptomatic and investigations are not helpful in the diagnosis. The advanced cancer is incurable and long term survival can be expected in incidentally found carcinoma of gall bladder