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Thallium-201 myocardial perfusion aspect: adenosine alone and adenosine combined with exercise
Specialist Quarterly. 1996; 13 (1): 11-20
in English | IMEMR | ID: emr-43469
ABSTRACT
To study whether combination of pharmacological stress test using Adenosine infusion with dynamic exercise of 25 watts, enhances the detection of Coronary Artery Disease. [CAD]

Design:

Prospective study involving 660 consecutive patients referred for myocardial perfusion SPECT.

Setting:

Punjab Institute of Cardiology, Lahore.

Subjects:

Of the referred 660 patients the first 160 patients under-went a pharmacological stress test using Adenosine only [Group A]. In the next 500 patients [Group B] adenosine infusion was combined with dynamic exercise of 25 watts for six minutes. Coronary Angiography results were available in 90 patients, 40 in Group A and 50 in Group B. Segmental analysis of thallium-201 SPECT revealed an overall sensitivity and specificity was similar in both groups [87% vs 90% and 84% vs 88% respectively]. For RCA lesions the sensitivity was 82% for Group A and 90% for Group B.

Conclusions:

Use of dynamic exercise in addition to Adenosine decreases the drug related side effects and it appears to be more sensitive in detection of RCA lesions
Subject(s)
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Index: IMEMR (Eastern Mediterranean) Main subject: Thallium / Exercise Test Language: English Journal: Specialist Q. Year: 1996

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Index: IMEMR (Eastern Mediterranean) Main subject: Thallium / Exercise Test Language: English Journal: Specialist Q. Year: 1996