Some of the clinico-biochemical effects of organophosphorus insecticides [phoxim] in rams

ABSTRACT

Two equal groups [group I and II] of healthy adult cross-bred rams were dipped in diluted Phoxim solution [1 2000]. The group II was injected with 5 ml of Catozal just before dipping. All rams were proved to have no troubles after dipping, whereas some attendant workers exposed diluted solution without care showed signs, including cough, irrigation of the nasopharyngeal mucosa, sneezing congestion of the eyelids with severe nasal discharge and lacrimation. Hematological analysis of rams revealed a significant increase of hematocrit in group I due to increased red cell mass [absolute polycythemia] after dipping. Biochemical investigation revealed a significant decrease of acetylcholinestrase [AChE] and albumin in groups I and II and a significant decrease of total protein in group I while a significant increase of glucose in groups I and II and a significant increase in the level of aspartate aminotransaminase [AST] activity, creatinine and blood urea nitrogen in groups I and II were recorded