Prophylactic and therapeutic efficacy of carbamazepine in psychosis

ABSTRACT

The objective of this study is to assess the effect of carbamazepine [CBZ] in psychotic disorders, and to find the predictors for its use. Forty-three patients with psychotic disorders were selected randomly from private clinic. The duration of their illness varied from two years to twenty years. CBZ started [after two weeks wash out from other antipsychotic medications] in increasing doses from 100- 600mg daily. The outcome of this study depends on the diagnosis and the duration of the psychotic illness, the shorter the duration the better the results. Affective psychoses shows better results than.schizophrenic psychoses, and in depressed schizophrenic patients, CBZ acts as an adjuvant antidepressant to their antipsychiatric medications. Follow up of these patients is still. going on