Heterogenous adhesion properties of pseudomonas aeruginosa strains to different athrocytes species

ABSTRACT

The property of Pseudomonas aeruginosa strains and isolates to hemagglutinate erythrocytes of human ABO-blood groups, rat, rabbit, ginea pig, mouse, bovine and ovine were investigated. The findings showed a heterogeneous behaviour among strains and isolates to hemagglutinate different erythrocyte species. The basic results showed that adhesion could be mediated both through mannose containing entity and non-mannose dependent entity. Evidence for the implication of both ligand and receptor operating both on bacterium and target erythrocyte is presented. There was no correlation between the presence of terminal mannose, as evidenced by FITC-con-A binding among the strains and isolates and the mannose sensitive adherence [hemagglutination]. The results are discussed based on the importance of such heterogeneous adherence mechanisms operating in Pseudomonas aeruginosa and the new trends of adhesion importance