New 4-substituted phenoxy quinolines of possible antimierobial activity

ABSTRACT

New series of semicarbazone and substituted thiosemicarbazones [3a-d], 7-chloro-4-[p-[4-aryl-3-cyano-2-oxo[1H] pyridin-6-yl] phenoxy] quinolines [4a-f], 7-chloro-4-[p-[4-aryl-3-cyano-2-imino[1H] pyridin-6-yl] phenoxy]quinolines [5a-e] and 7-chloro-4-[p-[4-aryl-3-cyano-2-thioxo [1H] pyridin-6-yl] phenoxy] quinoline [6a-c], were synthesized for the purpose of antimicrobial evaluation against Gram +ve, Gram -ve bacteria, yeast and fungi