Effect of yohimbine-Trazodone on psychogenic impotence

ABSTRACT

The aim of this study was to find out the effect and safety of Yohimbine-Trazodone used together for the treatment of psychogenic impotence. Forty patients who had psychogenic impotence diagnosed on the basis of sexual history, clinical examination, laboratory analysis, morning erection with full bladder were given an 8 weeks course of Yohimbine- Trazodone orally. Erectile function, ejaculation, interest in sex and sexual thoughts were investigated at the end of treatment and at 3 and 6 months follow up. Forty patients completed the whole treatment schedule, Positive clinical responses and improvement were obtained in 34 patients [85%] at the end of the treatment phase, were maintained in 28 patients [70%] and 25 patients [62.5%] at 3 and 6 months follow up,' respectively. No drug related adverse effects occurred. The combination of Yohimbine and Trazodone is an effective and safe treatment for psychogenic impotence