Isolation of [+] -tubocurarine and an unknown alkaloid from curare resin by a new chromatographic technique
Journal of Drug Research of Egypt. 1984; 15 (1-2): 235-243
in English
| IMEMR
| ID: emr-4538
ABSTRACT
This paper describes a new TLC method which gives an excellant resolution of the 12 alkaloids present in curare resin. The method is simple, suitable for isolation of [+]-tubocurarine alkaloid and the interferred unknown alkaloid in commercial curare resin. The unidentified laevorotatory alkaloid gives rise to particular problems in the production of pure d-tubocurarine chloride as it interferes in the crystallization process of d-tubocurarine. Pure crystalline [+]-tubocurarine and the unidentified alkaloid can be prepared by this method. It is also suitable for control analysis of commercial curare resin and [+]-tubocurarine chloride alkaloid
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Chromatography
/
Curare
Language:
English
Journal:
J. Drug Res. Egypt
Year:
1984
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