Serum fructosamine as a monitor of periodontal therapy in diabetics

ABSTRACT

The effect of nonsurgical periodontal therapy on diabetics was investigated in the present study. Metabolic conditions was monitored by measuring serum fructosamine [SF]. Forty-eight adult NIDDM patients were selected, they were suffering from periodontal problems. After medical evaluation diabetic patients were divided into two groups Moderate periodontitis group [periodontal disease index [PDI] between 3 and 4] and advanced periodontitis group PDI >4]. Gingival bleeding on probing [BoP], plaque index [PLI], serum fructosamine and blood glucose level were recorded to all diabetic patients before any periodontal therapy. The following periodontal treatment was then performed Oral hygiene instruction, ultrasonic instrumentation, debridement of periodontal pockets and professional subgingival irrigation. All clinical and laboratory parameters were re- estimated after one-month period. The results showed a significant reduction in BoP and PLI in both groups after periodontal therapy, while significant decrease of PDI was recorded in patients with moderate periodontitis only FA showed a significant reduction in both groups after periodontal therapy. The results showed a positive relation between improvement of periodontal condition and reduction of serum fructosamine as severe periodontitis exaggerates FA values in diabetics. Therefore, periodontal status of diabetic patient must be considered when monitoring hyperglycemia