Chlamydia trachomatis in chronic prostatitis

ABSTRACT

This study was done to elucidate the role of Chlamydia trachomatis in chronic prostatitis and its association with other conventional bacterial agents commonly accused as causing chronic prostatitis and to evaluate prostatic massage [PM] as a technique for diagnosis of chronic prostatitis. Also, the study evaluated two recently developed chlamydial antigen detection tests Clearview test [CV] [Unipath, Bedford, UK] and Chlamy-check-1 test [Veda-Lab, France] as compared with standard Direct Fluorescent Antibody [DFA] test [Kallestadt, Sweden] in male urine samples and expressed prostatic secretions [EPS]. The therapeutic effect of doxycycline regimen was assessed in treatment of chronic chlamydial prostatitis. From the results obtained it was concluded that C. trachomatis should be considered as an etiological agent in chronic prostatitis either solely or in combination with other bacteria. The low sensitivity of both CV and Chlamy-check-1 tests limit their diagnostic value on samples from men. DFA was the most reliable technique for detection of Chlamydia trachomatis giving on overall incidence of 55%. This emphasizes the important role of C. trachomatis in chronic prostatitis