Post-mortem diagnosis of renal failure

ABSTRACT

The present study was carried out on 100 Egyptian subjects, aged 17-75 years. They were classified into 4 groups Group I [n=20] included healthy subjectswith negative history of renal troubles, group II [n=20] included patientswith previous known history of uremia, and the last group included 60 cadaverswhich again divided into group III [n=18] included cadavers without provedrenal pathology, and group IV [n=24] included cadavers with proved renalpathological changes. Randomly collected blood samples from the wholesubjects as well as vitreous samples from both eyes of cadavers were used forthe estimation of urea, creatinine, uric acid, and G- glutamyl transpeptidaseactivities. In addition, wedge-shaped renal slices from both kidneys weretaken from cadavers to assure the diagnosis, and to make if possible acorrelation between the histopathologic findings and the biochemical results: