Impact of maternal hypertension on neonatal immunoglobulins [Ig]

ABSTRACT

The aim of this work was to study the effect of maternal hypertension [preeclampsia or essential hypertension PAH] and its impact on the Ig profile of cord blood. Fifty neonates were included, 25 target cases [babies born to mothers with pregnancy associates hypertension [PAH]] and 25 cases as a control group [neonates born to normal mothers]. The results revealed a difference as regards IgG in the control group compared with PAH [preeclampsia and essential hypertension]. Regarding the mode of delivery, IgG was higher [SS] in vaginal compared with CS. It is the gestational age and not the birth weigh which influenced the Ig level of the newborn. So, the control of maternal hypertension and nutritional support as well as vaginal delivery together with the prevention of prematurity will elevate the Ig level of the neonate to overcome the challenge of external environment