Multifocal glioblastoma: malignant progression in a glioma with unusual computed tomographic presentation

ABSTRACT

Glioblastoma multiforme rarely presents as multiple primary intracranial tumours in the absence of phakomatosis. An elderly lady presented with late onset seizures with persistent postictal deficit. She was investigated one year back for seizure with a CT scan and a lesion was noted in the left insular region without mass effect. No surgery was indicated. Repeat CT scan showed a metachronous multifocal tumour. She underwent excision of one of the lesions. Histology was consistent with glioblastoma multiforme. Other lesion could not be operated due to its precarious location. The case is reported for its unusual CT presentation and malignant progression